Classical and Bayesian Inference Assignment Help

Statistical parametric mapping (SPM) has been used to characterise neuroimaging data sequences since its inception. SPM, on the other hand, has limitations because it is based on classical inference procedures. This chapter introduces a more general framework for situating SPM in a broader context and pointing to alternative methods for characterising and inferring regionally specific effects in neuroimaging. The connection between classical inference and empirical Bayesian inference is established through covariance component estimation, and procedures used in conventional Classical and Bayesian Inference in terms of hierarchical linear models are developed. The EM algorithm is used to make this estimate. This chapter also emphasises the theory’s applications to a variety of important issues in neuroimaging. Estimating no sphericity or variance components in fMRI time series that can arise from serial correlations within subjects or that are induced by multi-subject studies is one of these issues. Bayesian models for imaging data are also included, in which effects at one voxel are constrained by responses in others.

KEY FEATURE

When only a small representative random sample of the population can be obtained, classical inference is used to estimate the statistical characteristics of a large population.

Understanding classical inference is necessary for understanding its strengths and how Bayesian inference and Dempster-Shafer evidential theory each alleviate some of its limitations.

The classical, or frequentist, paradigm and the Bayesian paradigm are the two major statistical paradigms that address statistical inference questions.

While most statistics and machine learning are based on the classical paradigm, Bayesian techniques are increasingly being adopted by the statistical and scientific communities.

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